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Chemical properties of 1,4-butyrolactone

Time:2021-05-20 Source: Yuyuan chemical Click:125

It is stable in neutral medium, easy to produce reversible hydrolysis in hot alkali and lactone when pH returns to neutral, but slow in acid medium.
[dissolution]
It is miscible with water and soluble in methanol, ethanol, ether, acetone, benzene and carbon tetrachloride
Note: it is flammable liquid, and avoid direct contact with fire source.
Toxicity: low toxicity. The oral LD50 of mice was 345 mg / kg.
There are many derivatives of 1,4-butyrolactone, which can produce different products through a variety of reactions
Hydrolyzable formation γ- Hydroxybutyric acid can be used as a special plasticizer of resin and pharmaceutical intermediate;
It can be oxidized to succinic acid; 4-hydroxybutyraldehyde was reduced to 1,4-butanediol;
Condensable generation α,α- Dihydroxy ketal;
It can react with CH3NH2 to form N-methyl-2-pyrrolidone;
Tetrahydrofuran can be formed;
It can react with SO3 to form butyrolactone- α- Sulfonic acid;
It can react with NaCN to form 2-piperidone;
It can react with CO to form glutaric acid;
It can react with NaOH to form 4,4-oxobutanoic acid;
It can react with Na2S to form thiosuccinic acid;
It can react with Na2SO3 γ- Sodium sulfobutyrate.